Hipoadrenocorticismo

Hipoadrenocorticismo or Enfermedad de Addison

It is a endócrina disease of little frequent presentation in the dog and still more in the cat characterized by a adrenocortical hypofunction (deficiency of the function of the crust of the suprarrenal gland).

The suprarrenal insufficiency, acute as as much chronic, pronounces with a sintomatología that this given by the absence or little glucocorticoid secretion or mineralocorticoids (hormones that must secretar the suprarrenal gland) have serious consequences, since these hormones are indispensable to conserve the arterial pressure, the volume, the homeostasis of the glucose and a great variety of vital functions for the life the basic characteristicses of the metabolic disorder are hipovolemia, arterial hypotension, lethargy and anorexy.
It mainly affects dogs (70-85%) adult, most of cases before the 7 years, do not know preferences by no race in individual.

It can be:
* Primary
Of primary due to a disease of the adrenal glands or secondary origin if there is a lack of adrenal stimulation of hipotalámico-hipofisario origin. The most frequent cause of spontaneous primary hipoadrenocorticismo is not known with exactitude but it seems to be that it is a inmunomediado upheaval affecting the adrenal ones and sometimes, simultaneously, other glands endócrinas. A secretion deficiency takes place in this case glucocorticoid and mineralocorticoid. Other causes you decipher are adrenal infections, infarcts, neoplasias, traumas and amiloidosis. Also cases of iatrogénico primary hipoadrenocorticismo as a result of the treatment of a hiperadrenocorticismo appear with or, p'- DDD.

* Secondary
The spontaneous secondary hipoadrenocorticismo must to diverse diseases that can affect to the hypothalamus or the hipófisis of inflammatory type, tumorlike or traumatic. The presentation of a iatrogénico secondary hipoadrenocorticismo is more frequent: one is generally in patients who have received glucocorticoids in high doses due to the administration of exogenous corticoesteroides when suppressing itself, although she is made with extreme caution, she can produce a suprarrenal hypofunction and to even exacerbar the underlying upheaval. In addition, if it adds conditions of estréss, the doses of steroid maintenance are sometimes insufficient.

Causes of Suprarrenal Insufficiency: